Our research bridges computational and experimental sciences to discover how RNA plays crucial roles across the human genome. We have discovered that RNA is required for numerous biological processes ranging from viability, fertility and development. We continually strive to bridge the computational and experimental sciences to discover new RNA genes such as long noncoding RNAs (lncRNA). This includes single-molecule RNA imaging, RNA-sequencing, Single Cell RNA-sequencing, and CRISPR-Display of RNA. Our multifaceted and cross-disciplinary approach has demonstrated the central role of RNA in nearly every biological system we have investigated.
Currently, we are harnessing the power of RNA and lncRNA to develop novel RNA therapeutics that could cure numerous human diseases. In fact, our research just launched a new biotech company called . aims to be a leader in new modalities of using lncRNA to "fix" disease genes. Learn more about LincSWITCH and our team at:.
on Google Scholar