3D resolution capabilities of two optical microscope systems. Ont he left is a confocal microscope 3D image that appears stretched in the vertical (axial) direction. On the right is a new 3D super-resolution method that correctly resolves all three dimensions. We study and develop optical microscopesÌýthat help biologists and engineers address their questionsÌýmore quantitatively and accurately, and we do so by extending the capability of optical imaging beyond traditionalÌýlimitations.​

Our research interests include extending the depth of field ofÌýimaging systems, increasing image resolution beyond Rayleigh's resolution criterion, and quantifyingÌýthe optical path length distributions of transparent objects. To exploreÌýthese topics, we utilize a wide range of innovative techniquesÌýsuch as point spread function engineering, differential interferometry, multiplexed optical scanning, computational imaging, andÌýnumerical optimization.

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