![Charles Hoeffer portrait](/ibg/sites/default/files/styles/small/public/people/charles_hoeffer_d.jpg?itok=p6bNiHc2)
Associate Professor
Institute for Behavioral Genetics • Integrative Physiology
Institute for Behavioral Genetics
ÀÖ²¥´«Ã½ Boulder
447 UCB
Boulder, CO 80309-0447
Research Interests:
Understanding the cellular and molecular basis for neurological disorder andÌýneurodegenerative disease.
Active Grants:
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NIA R01 AG064465-01 (MPI: Hoeffer, Link, Opp) 7/1/2019-6/30/2024. Sleep Disruption and Alzheimer's Disease Pathology. Role: PI
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NIA R01 AG064465-01 SUPPLEMENT2 (MPI: Hoeffer, Link, Opp) 8/1/2022-7/31/2024. Sleep Disruption and Alzheimer's Disease Pathology/ Links between AD, DS and sleep disruption. Role: PI
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AB Nexus Grant (MPI: Huntsman, Hoeffer) Period 12/1/2021-11/30/2022 Understanding AKT1 function regulating interneuronal activity involved in E/I balance.ÌýRole: PI
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NIDA R21/R33 DA055781-A1 (Hoeffer, Ehringer, Stitzel) 9/15/2022-9/14/2027. Role of glial expression in nicotine behaviors for genes identified through human GWAS Role: PI
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NIA RF1AG064465-S2 (Hoeffer, Opp, Link) 04/01/2022-3/31/2023 Sleep Disruption in Down Syndrome-related Alzheimer’s Disease. Role: PI
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Lab Venture Challenge (LVC), Venture Partners at CU Boulder and the Colorado Office of Economic Development and International Trade (OEDIT) Advanced Industries Program, (MPI Hoeffer, Parker, Van Alstyne) 3/1/2024-2/28/2026. New treatment for dementia with peptide therapeutics targeting tau aggregation. Role: PI
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NI23013. AFAR (Evans) 01/01/2024-12/31/2026 ,Gene-gene interaction associations with frailty to identify core genes of aging and their biological context. Role: Co-Investigator
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NIH R01 AG083268 (Hoeffer) 9/1/2023-8/31/2028. Sleep abnormalities in Down Syndrome-related Alzheimer's disease. Role: PI
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NIH R01 NS131660 (Whiteley) 4/1/2023-3/31/2027. Investigation of UBQLN2-dependent changes to neuronal health and function in ALS-FTD. Role: Co-Investigator