Publications

Cozzolino, K; Sanford, L; Hunter, S; Molison, K; Erickson, B; Jones, T; Courvan, MCS; Ajit, D; Galbraith, MG; Espinosa, JM; Bentley, DL; Allen, MA; Dowell, RD; Taatjes, DJ.  eLife 2024, 13: RP100197.

Maia-Silva, D; Cuniff, PJ; Schier, AC; Skopelitis, D; Trousdell, MC; Moresco, P; Gao, Y; Kechejian, V; He, XY; Sahin, Y; Wan, L; Alpsoy, A; Liverpool, J; Krainer, AR; Egeblad, M; Spector, DL; Fearon, DT; Dos Santos, CO; Taatjes, DJ; Vakoc, CR.  Nat Genet 2024, 56: 1377 - 1385.  

Nussbaum, DP; Martz, CA; Waters, AM; Barrera, A; Rutter, JC; Cerda-Smith CG; Stewart, AE; Wu, C; Cakir, M; Levandowski, CB; Kantrowitz, DE; McCall, SJ; Pierobon, M; Petricoin, EF; Smith, JJ; Reddy, TE; Der, C; Taatjes, DJ; Wood, KC.  NPJ Precis Oncol 2024, 8: 124.

Richter, WF; Taatjes, DJ. Mol Cell 2024, 84: 1180 - 1182. 

Johnson, JL; Yaron, TM; Huntsman, EM; Kerelsky, A; Song, J; Regev, A; Lin, T-Y; Liberatore, K; Cizin, DM; Cohen, BM; Vasan, N; Ma, Y; Krismer, K; Torres Robles, J; van de Kooij, B; van Klimmeren, AE; Andree-Busch, N; Kaufer, N; Dorovkov, MV; Ryazanov, AG; Takagi, Y; Kastenhuber, ER; Goncalves, MD; Hopkins, BD; Elemento, O; Taatjes, DJ; Maucuer, A; Yamashita, A; Degterev, A; Linding, R; Blenis, J; Hornbeck, PV; Turk, BE; Yaffe, MB; Cantley, LC.  Nature 2023, 613: 759 - 766.  

Nayak, S; Taatjes DJ.  Cell 2022, 185: 3458.

Bassett, J; Rimel, JK; Basu, S; Basnet, P; Luo, J; Engel, KL; Nagel, MT; Woyciehowsky, A; Ebmeier, CC; Kaplan, CD; Taatjes, DJ; Ranish, JA.  J Biol Chem 2022, 102433.  

Clopper, KC; Taatjes, DJ.  Curr Opin Chem Biol 2022, 70: 102186.  

Richter, WF; Nayak, S; Iwasa, J; Taatjes, DJ.  Nat Rev Mol Cell Biol 2022, 23: 732 - 749.

Allen, BL; Quach, K; Jones, T; Levandowski, CB; Ebmeier, CC; Rubin, JD; Read, T; Dowell, RD; Schepartz, A*; Taatjes, DJ*.   Cell Rep 2022, 39: 110630.

Luyties, O; Taatjes, DJ.  . Trends Biochem Sci 2022, 47: 314 - 327.

Palacio, M; Taatjes DJ.  J Mol Biol 2022, 433: 167216.  

Levandowski, CB; Jones, T; Gruca, M; Ramamoorthy, S; Dowell, RD;* Taatjes, DJ.*   PLoS Biol 2021, 19: e3001364.  

Schier, AC; Taatjes, DJ.  Nat Struct Mol Biol 2021, 28: 540 - 543.  

Rubin, JD; Stanley, JT; Sigauke, RS; Levandowski, CB; Maas, ZL; Westfall, J; Taatjes, DJ; Dowell, RD.  Commun Biol 2021, 4: 661.

Taatjes, DJ.  J Mol Biol 2021, 433: 167037.

Tomko, EJ; Luyties, O; Rimel, JK; Tsai, C; Fuss, JO; Fishburn, J; Hahn, S; Tsutakawa, SE; Taatjes, DJ; Galburt, EA.  J Mol Biol 2021; 433: 166813.  

Rimel, JK; Poss, ZC; Erickson, B; Maas, ZL; Ebmeier, CC; Johnson, JL; Decker, T-M; Yaron, TM; Bradley, MJ; Hamman, KB; Hu, S; Malojcic, G; Marineau, JJ; White, PW; Brault, M.; Tao, L.; DeRoy, P; Clavette, C; Nayak, S; Damon, LJ; Kaltheuner, IH; Bunch, H; Cantley, LC; Geyer, M; Iwasa, J; Dowell, RD; Bentley, DL; Old WM;* Taatjes, DJ.*   Genes Dev 2020; 34: 1452 – 1473.  

Klein, IA; Boija, A; Afeyan, LK; Hawken, SW; Fan, M; Dall’Agnese, A; Oksuz, O; Henninger, JE; Shrinivas, K; Sabari, BR; Sagi, I; Clark, V; Platt, J; Kar, M; McCall, P; Zamudio, AV; Manteiga, JC; Coffey, EL; Li, CH; Hannett, NM; Guo, YE; Decker, TM; Lee, TI; Zhang, T; Weng, JK; Taatjes, DJ; Chakraborty, A; Sharp, PA; Chang, YT; Hyman, AA; Gray, NS; Young, RA.  Science 2020, 368: 1386 – 1392.

Fant, CB; Levandowski, CB; Gupta, K; Maas, ZL; Moir, JT; Rubin, JD; Sawyer, A; Esbin, M; Rimel, JK; Luyties, O; Marr, MT; Berger, I; Dowell, RD; Taatjes, DJ. Mol Cell 2020, 78: 785 – 793.

Schier, AC; Taatjes, DJ. Genes Dev. 2020, 34: 465 – 488.

Zamudio, AV; Dall’Agnese, A; Henninger, JE; Manteiga, JC; Afeyan, LK; Hannett, NM; Coffey, EL; Li, CH; Oksuz, O; Boija, A; Klein, IA; Sabari, BR; Hawken, SW; Spille, JH; Decker, TM; Cisse, II; Abraham, BJ; Lee, TI; Taatjes, DJ; Schuijers, J; Young, RA. Mol Cell 2019, 76: 753 – 766.

Steinparzer, I; Sedlyarov, V; Rubin, JD; Eislmayr, K; Galbraith MD; Levandowski, CB; Vcelkova, T; Sneezum, L; Wascher, F; Amman, F; Kleinova, R; Bender, H; Andrysik, Z; Espinosa, JM; Superti-Furga, G; Dowell, RD; Taatjes, DJ;* Kovarik, P.*  Mol Cell 2019, 76: 485 â€“ 499. 

Guo, YE; Manteiga, JC; Henninger, J; Sabari, BR; Dall'Agnese, A; Hannett, NM; Spille, J-H; Afeyan, LK; Zamudio, AV;  Shrinivas, K; Abraham, BJ; Boija, A; Decker, TM; Rimel, JK; Fant, CB; Lee, TI; Cisse, II; Sharp, PA; Taatjes, DJ; Young, RA. . Nature 2019, 572: 543 – 548. 

Fant, CB; Taatjes, DJ. . Transcription 2019, 10: 76 – 90.  

Guard, SE; Poss, ZC; Ebmeier, CC; Pagratis, M; Simpson, H; Taatjes, DJ; Old, WM. . Sci Rep. 2019, 9: 6539. 

Harper, TM; Taatjes, DJ. . J Biol Chem. 2018, 293: 13778-13785.

Boija, A; Klein, IA; Sabari, BR; Dall'Agnese, A; Coffey, EL; Zamudio, AV; Li, CH; Shrinivas, K; Manteiga, J; Hannett, NM; Abraham, BJ; Schuijers, J; Afeyan, L; Guo, YE; Rimel, JK; Fant, CB; Lee, TI; Taatjes, DJ; Young, RA. . Cell 2018, 175: 1842-1855.

Goodrich JA; Taatjes DJ. . Nature 2018, 558: 197-198.

Rimel, JK; Taatjes DJ. . Protein Sci. 2018, 27: 1018-1037.

Xiaoyang Guan, Patrick K. Chaffey, Yuan Ruan, Connor K. Hurd, Dylan J. Taatjes, Zhongping Tan. . Synlett 2017; 28: 1917-1922.

Taatjes, DJ. . Mol Cell 2017, 68: 1-2.

Taatjes, DJ. . J Mol Biol. 2017, 429: 2996-2998.

Ebmeier, CC; Erickson, B; Allen, BL; Allen, MA; Kim, H; Fong, N; Jacobsen, JR; Liang, K; Shilatifard, A; Dowell, RD; Old, WM; Bentley, DL*; Taatjes, DJ*. . Cell Rep.  2017, 20:  1173 - 1186.

Audetat, KA; Galbraith, MD; Odell, AT; Lee, T; Pandey, A; Espinosa, JM; Dowell, RD; Taatjes, DJ. . Mol Cell Biol. 2017, 37: e00626-16.

Alhadid, Y; Chung, S; Lerner, E; Taatjes, DJ; Borukhov, S; Weiss, S. . Protein Sci. 2017, 26: 1278 - 1290.

Lerner, E; Chung, S; Allen, BL; Wang, S; Lee, JJ; Lu, SW; Grimaud, LW; Ingargiola, A; Michalet, X; Alhadid, Y; Borukhov, S; Strick, T;* Taatjes, DJ;* Weiss, S.* . Proc Natl Acad Sci. USA. 2016, E6562 – E6571.  

Passmore LA; Taatjes DJ. . J Mol Biol. 2016, 428: 2539 - 2541.

Poss, ZC; Ebmeier, CC; Odell, AT; Tangpeerachaikul, A; Lee, T; Pelish, HE; Shair, MD; Dowell, RD; Old, WM; Taatjes, DJ.  . Cell Rep. 2016, 15: 436 - 450.

Rubin, JD; Taatjes, DJ.  . Nature 2015, 526: 199 - 200.

Luo, J; Cimermancic, P; Viswanath, S; Ebmeier, CC; Kim, B; Dehecq, M; Raman, V; Sali, A; Taatjes, DJ; Hahn, S; Ranish, J. . Mol Cell 2015, 59: 794 - 806.  

Fant, CB; Taatjes DJ. .  Mol Cell  2015, 57: 952 - 954.  

Pelish, HE; Liau, BB; Nitulescu, I; Tangpeerachaikul, A; Poss, ZC; DaSilva, D; Caruso, B; Arefolov, A; Fadeyi, O; Christie, A; Du, K; Banka, D; Schneider, EV; Jestel, A; Zou, G; Si, C; Ebmeier, CC; Bronson, RT; Krivtsov, AV; Myers, AG; Kohl, N; Kung, A; Armstrong, S; Lemieux, M; Taatjes, DJ; Shair, MD. . Nature 2015, 526: 273 - 276.

Allen, BL; Taatjes, DJ. . Nat Rev Mol Cell Biol. 2015, 16: 155 - 166.

Bunch, H; Zheng, X; Burkholder, A; Dillon, S; Motola, S; Birrane, G; Ebmeier, CC; Levine, S; Fargo, D; Hu, G; Taatjes, DJ; Calderwood, SK. Nat Struct Mol Biol. 2014, 21: 876 - 883.

Sennett, NC; Taatjes, DJ. Cell Res.  2014 24: 775 - 776.

Lin, SC; Taatjes, DJ. .  Aging (Albany NY)  2013 5: 717 - 718.

Poss, ZC; Ebmeier, CC; Taatjes, DJ. Crit Rev Biochem Mol Biol. 2013, 48: 575 - 608.

Lin, SC; Karoly, ED; Taatjes, DJ. . Aging Cell 2013, 12: 863 - 872.

Phillips, A; Taatjes, DJ. . Isr J Chem. 2013, 53: 588 - 595.

He, Y; Fang, J; Taatjes, DJ; Nogales, E.  Nature 2013, 495: 481 - 486.

Lai, F; Orom, UA; Cessaroni, M; Beringer, M; Taatjes, DJ; Blobel, G; Shiekhattar, R. Nature 2013, 494: 497 - 501.

Davis, MA; Larimore, EA; Fissel, BM; Swanger, J; Taatjes, DJ; Clurman, BE. . Genes Dev. 2013, 27: 151 - 156.

Bancerek, J; Poss, ZC; Steinparzer, I; Sedlyarov, V; Pfaffenwimmer, T; Mikulic, I; Dolken, L; Strobl, B; Muller, M; Taatjes, DJ; Kovarik, P. . Immunity 2013, 38: 250 - 262.

Schwartz, J; Ebmeier, CC; Podell, EA; Heimiller, J; Taatjes, DJ; Cech, TR. . Genes Dev. 2012, 26: 2690 - 2695.

Bernecky, C; Taatjes, DJ. . J Mol Biol. 2012, 417: 387 - 394. 

Taylor, DJ; Podell, EA; Taatjes, DJ; Cech, TR. . J Mol Biol. 2011, 410: 10 - 17.

Bernecky, C; Grob, P; Ebmeier, CC; Nogales, E; Taatjes, DJ. . PLoS Biol. 2011, 9: e1000603.

Knuesel, MT; Taatjes, DJ. . Transcription 2011, 2: 28 - 31.

Kagey, MH; Newman, JJ; Bilodeau, S; Zhan, Y; Orlando, DA; van Berkum, NL; Ebmeier, CC; Goossens, J; Rahl, PB; Levine, SS; Taatjes, DJ*; Dekker, J*; Young, RA*. . Nature 2010, 467: 430 - 435.

De Carlo, S; Lin, S; Taatjes, DJ; Hoenger, A. .Transcription 2010, 1: 103 - 111.

Ebmeier, CC; Taatjes, DJ. . Proc Natl Acad Sci. USA. 2010, 107: 11283 - 11288.

Meyer, KD; Lin, S; Bernecky, C; Gao, Y; Taatjes, DJ. . Nat Struct Mol Biol. 2010, 17: 753 - 760.

Taatjes, DJ. . Trends Biochem Sci. 2010, 35: 315 - 322.

Donner, AJ; Ebmeier, CC; Taatjes, DJ; Espinosa, JM. . Nat Struct Mol Biol. 2010, 17: 194 - 201.

Knuesel, MT; Meyer, KD; Bernecky, C; Taatjes, DJ. .  Genes & Dev. 2009, 23: 439 - 451. 

Knuesel, MT; Meyer, KD; Donner, AJ; Espinosa JM; Taatjes, DJ. . Mol Cell Biol. 2009, 29: 650 - 661.

Panning, B; Taatjes, DJ. . Mol Cell 2008, 31: 622 - 629.

Meyer, KD; Donner, AJ; Knuesel, MT; York, AG; Espinosa, JM; Taatjes, DJ. . EMBO J 2008, 27: 1447 - 1457.

Taatjes, DJ; Marr, MT; Tjian, R. Regulatory diversity among metazoan co-activator complexes. Nat RevMol Cell Biol. 2004, 5: 403 - 410.

Taatjes, DJ; Schneider-Poetsch, T; Tjian, R. Distinct conformational states of nuclear receptor-bound CRSP–Med complexes. Nat Struct Mol Biol. 2004, 11: 664 - 671.

Taatjes, DJ; Tjian, R. Structure and function of CRSP/Med2: a promoter-selective transcriptional coactivator complex. Mol Cell 2004, 14: 675 - 683.

Taatjes, DJ; Näär, AM; Andel, F; Nogales, E; Tjian, R. Structure, function, and activator-induced conformations of the CRSP coactivator. Science 2002, 295: 1058 - 1062.

Näär, AM;Taatjes, DJ; Zhai, W; Tjian, R. Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation. Genes Dev. 2002, 16: 1339 - 1344.

Dernell, WS; Powers, BE; Taatjes, DJ; Cogan, P; Gaudiano, G; Koch, TH. Evaluation of the epidoxorubicin-formaldehyde conjugate, Epidoxoform, in a mouse mammary carcinoma model. Cancer Invest. 2002, 20: 712 - 723.

Taatjes, DJ; Koch, TH. Nuclear targeting and retention of anthracycline antitumor drugs in sensitive and resistant tumor cells. Curr. Med. Chem. 2001, 8: 15 - 29.

Kato, S; Burke, PJ; Fenick, DJ; Taatjes, DJ; Bierbaum, VM; Koch, TH. Mass spectrometric measurement of formaldehyde generated in breast cancer cells upon treatment with anthracycline antitumor drugs. Chem. Res. Toxicol. 2000, 13: 509 - 516.

Taatjes, DJ; Koch, TH. Growth inhibition, nuclear uptake, and retention of anthracycline-formaldehyde conjugates in prostate cancer cells relative to clinical anthracyclines.  Anticancer Res. 1999, 19: 1201 - 1208.

Podell, E; Harrington, D; Taatjes, DJ; Koch, TH. Crystal structure of Epidoxorubicin-formaldehyde virtual crosslink to DNA and evidence of its formation in human breast cancer cells. Acta Cryst. 1999, D55: 1516 - 1523.

Taatjes, DJ; Fenick, DJ; Koch, TH. Nuclear targeting and nuclear retention of anthracycline-formaldehyde conjugates implicates DNA covalent bonding in the cytotoxic mechanism of anthracyclines. Chem. Res. Toxicol. 1999, 12: 588 - 596. [Cover]

Taatjes, DJ; Fenick, DJ; Gaudiano, G; Koch, TH. A redox pathway leading to the alkylation of nucleic acids by doxorubicin and related anthracyclines: application to the design of antitumor drugs for resistant cancer. Curr. Pharm. Des. 1998, 4: 217 - 232.

Taatjes, DJ; Fenick, DJ; Koch, TH. Epidoxoform: a hydrolytically more stable anthracycline-formaldehyde conjugate, toxic to resistant tumor cells.  J. Med. Chem. 1998, 41: 1306 - 1314.

Taatjes, DJ; Gaudiano, G; Resing, K; Koch, TH. A redox pathway leading to the alkylation of DNA by the anthracycline, antitumor drugs, Adriamycin and Daunomycin.  J. Med. Chem. 1997, 40: 1276 - 1286.

Fenick, DJ; Taatjes, DJ; Koch, TH. Doxoform and Daunoform: anthrcycline-formaldehyde conjugates toxic to resistant tumor cells. J. Med. Chem. 1997, 40: 2452 - 2461.

Taatjes, DJ; Gaudiano, G; Koch, TH. Production of formaldehyde and DNA-adriamycin or –daunomycin adducts, initiated through redox chemistry of DTT/iron, xanthine oxidase/NADH/iron, or glutathione/iron.Chem. Res. Toxicol. 1997, 10: 953 - 961.

Taatjes, DJ; Gaudiano, G; Resing, K; Koch, TH. Alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin. J. Med. Chem. 1996, 39: 4135 - 4138.